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c-myc gene inactivation during induced maturation of HL-60 cells. Transcriptional repression and loss of a specific DNAse I hypersensitive site.

The c-myc proto-oncogene is amplified and expressed at high levels in HL-60 cells, a cell line derived from a patient with acute promyelocytic leukemia. Upon induction to terminal maturation, expression of c-myc is greatly reduced. We have studied the level of gene expression at which the change in...

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Bibliografski detalji
Glavni autori: High, K A, Stolle, C A, Schneider, J W, Hu, W, Benz, E J
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC423994/
https://ncbi.nlm.nih.gov/pubmed/3540012
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