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Tumor necrosis factor inhibits MYC expression in HL-60 cells at the level of mRNA transcription.

Highly purified, recombinant human tumor necrosis factor type alpha (rTNF-alpha) exerts cytostatic activity on the human promyelocytic leukemic cell line HL-60. Between 4 and 10 hr after treatment with rTNF-alpha, HL-60 cells start to exhibit phagocytic activity, indicating the induction of a differ...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Krönke, M, Schlüter, C, Pfizenmaier, K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304229/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3099296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.2.469
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