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Intracellular pH modulates the generation of superoxide radicals by human neutrophils.

The relationship of intracellular pH (pHi) to superoxide radical (O2-) generation was investigated in chemotactic factor-stimulated human neutrophils. Exposure of cells to 100 nM N-formylmethionyl-leucyl-phenylalanine (FMLP) caused activation of Na/H exchange which, in 140 mM Na medium (pH0 7.40), l...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Autor principal: Simchowitz, L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423992/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2995444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112061
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