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Intracellular pH modulates the generation of superoxide radicals by human neutrophils.
The relationship of intracellular pH (pHi) to superoxide radical (O2-) generation was investigated in chemotactic factor-stimulated human neutrophils. Exposure of cells to 100 nM N-formylmethionyl-leucyl-phenylalanine (FMLP) caused activation of Na/H exchange which, in 140 mM Na medium (pH0 7.40), l...
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| Udgivet i: | J Clin Invest |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1985
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2995444/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112061 |
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