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Intracellular pH modulates the generation of superoxide radicals by human neutrophils.

The relationship of intracellular pH (pHi) to superoxide radical (O2-) generation was investigated in chemotactic factor-stimulated human neutrophils. Exposure of cells to 100 nM N-formylmethionyl-leucyl-phenylalanine (FMLP) caused activation of Na/H exchange which, in 140 mM Na medium (pH0 7.40), l...

詳細記述

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書誌詳細
出版年:J Clin Invest
第一著者: Simchowitz, L
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423992/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2995444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112061
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