Lanean...
A PTCH1 Homolog Transcriptionally Activated by p53 Suppresses Hedgehog Signaling
The p53-mediated responses to DNA damage and the Hedgehog (Hh) signaling pathway are each recurrently dysregulated in many types of human cancer. Here we describe PTCH53, a p53 target gene that is homologous to the tumor suppressor gene PTCH1 and can function as a repressor of Hh pathway activation....
Gorde:
| Argitaratua izan da: | J Biol Chem |
|---|---|
| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2014
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239647/ https://ncbi.nlm.nih.gov/pubmed/25296753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597203 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|