Pharmacokinetic and Pharmacodynamic Properties of Calaspargase Pegol Escherichia coli L-Asparaginase in the Treatment of Patients With Acute Lymphoblastic Leukemia: Results From Children's Oncology Group Study AALL07P4

PURPOSE: Asparaginase is a critical agent used to treat acute lymphoblastic leukemia (ALL). Pegaspargase (SS-PEG), a pegylated form of Escherichia coli L-asparaginase with a succinimidyl succinate (SS) linker, is the first-line asparaginase product used in Children's Oncology Group (COG) ALL tr...

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Publicado en:J Clin Oncol
Autores principales: Angiolillo, Anne L., Schore, Reuven J., Devidas, Meenakshi, Borowitz, Michael J., Carroll, Andrew J., Gastier-Foster, Julie M., Heerema, Nyla A., Keilani, Taha, Lane, Ashley R., Loh, Mignon L., Reaman, Gregory H., Adamson, Peter C., Wood, Brent, Wood, Charlotte, Zheng, Hao W., Raetz, Elizabeth A., Winick, Naomi J., Carroll, William L., Hunger, Stephen P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2014
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ORIGINAL REPORTS
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239306/
https://ncbi.nlm.nih.gov/pubmed/25348002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.55.5763
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