Pharmacokinetic and Pharmacodynamic Properties of Calaspargase Pegol Escherichia coli L-Asparaginase in the Treatment of Patients With Acute Lymphoblastic Leukemia: Results From Children's Oncology Group Study AALL07P4

PURPOSE: Asparaginase is a critical agent used to treat acute lymphoblastic leukemia (ALL). Pegaspargase (SS-PEG), a pegylated form of Escherichia coli L-asparaginase with a succinimidyl succinate (SS) linker, is the first-line asparaginase product used in Children's Oncology Group (COG) ALL tr...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Angiolillo, Anne L., Schore, Reuven J., Devidas, Meenakshi, Borowitz, Michael J., Carroll, Andrew J., Gastier-Foster, Julie M., Heerema, Nyla A., Keilani, Taha, Lane, Ashley R., Loh, Mignon L., Reaman, Gregory H., Adamson, Peter C., Wood, Brent, Wood, Charlotte, Zheng, Hao W., Raetz, Elizabeth A., Winick, Naomi J., Carroll, William L., Hunger, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2014
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239306/
https://ncbi.nlm.nih.gov/pubmed/25348002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.55.5763
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