Compartmentalization of SIV Replication Within Secondary Lymphoid Tissues of Rhesus Macaques is Linked to Disease Stage and Inversely Related to Localization of Virus-Specific CTL

We previously demonstrated that HIV replication is concentrated in lymph node B cell follicles during chronic infection and that HIV-specific CTL fail to accumulate in large numbers at those sites. It is unknown whether these observations can be generalized to other secondary lymphoid tissues, or wh...

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Publicat a:J Immunol
Autors principals: Connick, Elizabeth, Folkvord, Joy M., Lind, Katherine T., Rakasz, Eva G., Miles, Brodie, Wilson, Nancy A., Santiago, Mario L., Schmitt, Kimberly, Stephens, Edward B., Kim, Hyeon O., Wagstaff, Reece, Li, Shengbin, Abdelaal, Hadia M., Kemp, Nathan, Watkins, David I., MaWhinney, Samantha, Skinner, Pamela J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239212/
https://ncbi.nlm.nih.gov/pubmed/25362178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401161
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