Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection

CD8+ T cells play an important role in controlling of HIV and SIV infections. However, these cells are largely excluded from B cell follicles where HIV and SIV producing cells concentrate during chronic infection. It is not known, however, if antigen-specific CD8+ T cells are excluded gradually as p...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Li, Shengbin, Folkvord, Joy M., Kovacs, Katalin J., Wagstaff, Reece K., Mwakalundwa, Gwantwa, Rendahl, Aaron K., Rakasz, Eva G., Connick, Elizabeth, Skinner, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445460/
https://ncbi.nlm.nih.gov/pubmed/30897187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007311
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