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Tumor-derived alpha-fetoprotein impairs the differentiation and T cell stimulatory activity of human dendritic cells
Several tumor-derived factors have been implicated in DC dysfunction in cancer patients. Alpha-fetoprotein (AFP) is an oncofetal antigen that is highly expressed in abnormalities of prenatal development and several epithelial cancers, including hepatocellular carcinoma (HCC). In HCC patients exhibit...
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| Publicado no: | J Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239186/ https://ncbi.nlm.nih.gov/pubmed/25355916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400725 |
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