Human dendritic cells adenovirally-engineered to express three defined tumor antigens promote broad adaptive and innate immunity

Dendritic cell (DC) immunotherapy has shown a promising ability to promote anti-tumor immunity in vitro and in vivo. Many trials have tested single epitopes and single antigens to activate single T cell specificities, and often CD8(+) T cells only. We previously found that determinant spreading and...

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Bibliografiske detaljer
Main Authors: Blalock, LeeAnn T., Landsberg, Jennifer, Messmer, Michelle, Shi, Jian, Pardee, Angela D., Haskell, Ronald, Vujanovic, Lazar, Kirkwood, John M., Butterfield, Lisa H.
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382861/
https://ncbi.nlm.nih.gov/pubmed/22737604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.18628
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