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Regulation of antigen presentation machinery in human dendritic cells by recombinant adenovirus

Recombinant adenoviral vectors (AdV) are potent vehicles for antigen engineering of dendritic cells (DC). DC engineered with AdV to express full length tumor antigens are capable stimulators of antigen-specific polyclonal CD8+ and CD4+ T cells. To determine the impact of AdV on the HLA class I antig...

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Autores principales: Vujanovic, Lazar, Whiteside, Theresa L., Potter, Douglas M., Chu, Jessica, Ferrone, Soldano, Butterfield, Lisa H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726804/
https://ncbi.nlm.nih.gov/pubmed/18488218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0533-2
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