Adenovirus MART-1–engineered Autologous Dendritic Cell Vaccine for Metastatic Melanoma

We performed a phase 1/2 trial testing the safety, toxicity, and immune response of a vaccine consisting of autologous dendritic cells (DCs) transduced with a replication-defective adenovirus (AdV) encoding the full-length melanoma antigen MART-1/Melan-A (MART-1). This vaccine was designed to activa...

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Hauptverfasser: Butterfield, Lisa H., Comin-Anduix, Begonya, Vujanovic, Lazar, Lee, Yohan, Dissette, Vivian B., Yang, Jin-Quan, Vu, Hong T., Seja, Elizabeth, Oseguera, Denise K., Potter, Douglas M., Glaspy, John A., Economou, James S., Ribas, Antoni
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651040/
https://ncbi.nlm.nih.gov/pubmed/18317358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31816a8910
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