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Cytomegalovirus Enhances Macrophage TLR Expression and MyD88-mediated Signal Transduction to Potentiate Inducible Inflammatory Responses

Circulating monocytes carrying human cytomegalovirus (HCMV) migrate into tissues, where they differentiate into HCMV-infected resident macrophages that upon interaction with bacterial products may potentiate tissue inflammation. Here we investigated the mechanism by which HCMV promotes macrophage-or...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Smith, Phillip D., Shimamura, Masako, Musgrove, Lois, Dennis, Evida A., Bimczok, Diane, Novak, Lea, Ballestas, Mary, Fenton, Anne, Dandekar, Satya, Britt, William J., Smythies, Lesley E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239158/
https://ncbi.nlm.nih.gov/pubmed/25355920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302608
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