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Metabolic Profiling and Flux Analysis of MEL-2 Human Embryonic Stem Cells during Exponential Growth at Physiological and Atmospheric Oxygen Concentrations

As human embryonic stem cells (hESCs) steadily progress towards regenerative medicine applications there is an increasing emphasis on the development of bioreactor platforms that enable expansion of these cells to clinically relevant numbers. Surprisingly little is known about the metabolic requirem...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Turner, Jennifer, Quek, Lake-Ee, Titmarsh, Drew, Krömer, Jens O., Kao, Li-Pin, Nielsen, Lars, Wolvetang, Ernst, Cooper-White, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239018/
https://ncbi.nlm.nih.gov/pubmed/25412279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112757
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