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A depth-first search algorithm to compute elementary flux modes by linear programming

BACKGROUND: The decomposition of complex metabolic networks into elementary flux modes (EFMs) provides a useful framework for exploring reaction interactions systematically. Generating a complete set of EFMs for large-scale models, however, is near impossible. Even for moderately-sized models (<4...

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Bibliographic Details
Published in:BMC Syst Biol
Main Authors: Quek, Lake-Ee, Nielsen, Lars K
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236763/
https://ncbi.nlm.nih.gov/pubmed/25074068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0094-2
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