Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid.
An amplification of tandem CAG trinucleotide sequences in DNA due to errors in DNA replication is involved in at least four hereditary neurodegenerative diseases. The CAG triplet repeats when translated into protein give rise to tracts of glutamine residues, which are a prominent feature of many tra...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1995
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7892196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.6.1901 |
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