Double-stranded DNA templates can induce alpha-helical conformation in peptides containing lysine and alanine: functional implications for leucine zipper and helix-loop-helix transcription factors.

Transcription factors of the basic-leucine zipper and basic-helix-loop-helix families specifically recognize DNA by means of intrinsically flexible peptide domains that assume an alpha-helical conformation upon binding to target DNA sequences. We have investigated the nonspecific interactions that u...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Johnson, N P, Lindstrom, J, Baase, W A, von Hippel, P H
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43884/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8197144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.4840
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