Markedly increased circulating pyridoxal-5'-phosphate levels in hypophosphatasia. Alkaline phosphatase acts in vitamin B6 metabolism.

Markedly increased circulating concentrations of pyridoxal-5'-phosphate (PLP) were found in each of 14 patients representing all clinical forms of hypophosphatasia, an inborn error characterized by deficient activity of the tissue nonspecific (bone/liver/kidney) isoenzyme of alkaline phosphatas...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Whyte, M P, Mahuren, J D, Vrabel, L A, Coburn, S P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1985
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423894/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4031070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112031
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