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Defining the Limits: Protein Aggregation and Toxicity In vivo

The proper folding of proteins to their functional forms is essential to cellular homeostasis. Perhaps not surprisingly, cells have evolved multiple pathways, some overlapping and others complementary, to resolve misfolded proteins when they arise, ranging from refolding through the action of molecu...

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Detalhes bibliográficos
Publicado no:Crit Rev Biochem Mol Biol
Main Authors: Holmes, William M., Klaips, Courtney L., Serio, Tricia R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238936/
https://ncbi.nlm.nih.gov/pubmed/24766537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2014.914151
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