Acute exercise modifies titin phosphorylation and increases cardiac myofilament stiffness

Titin-based myofilament stiffness is largely modulated by phosphorylation of its elastic I-band regions N2-Bus (decreases passive stiffness, PT) and PEVK (increases PT). Here, we tested the hypothesis that acute exercise changes titin phosphorylation and modifies myofilament stiffness. Adult rats we...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Physiol
Prif Awduron: Müller, Anna E., Kreiner, Matthias, Kötter, Sebastian, Lassak, Philipp, Bloch, Wilhelm, Suhr, Frank, Krüger, Martina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2014
Pynciau:
Physiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238368/
https://ncbi.nlm.nih.gov/pubmed/25477822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00449
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