Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension

Pulmonary arterial hypertension is a major complication of systemic sclerosis. Although oxidative stress, intima hyperplasia and a progressive vessel occlusion appear to be clearly involved, the fine molecular mechanisms underpinning the onset and progression of systemic sclerosis-associated pulmona...

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Sparad:
Bibliografiska uppgifter
I publikationen:Orphanet J Rare Dis
Huvudupphovsmän: Boin, Francesco, Erre, Gian Luca, Posadino, Anna Maria, Cossu, Annalisa, Giordo, Roberta, Spinetti, Gaia, Passiu, Giuseppe, Emanueli, Costanza, Pintus, Gianfranco
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2014
Ämnen:
Letter to the Editor
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237898/
https://ncbi.nlm.nih.gov/pubmed/25085432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-014-0123-7
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