Bioavailability, distribution and clearance of tracheally-instilled and gavaged uncoated or silica-coated zinc oxide nanoparticles

BACKGROUND: Nanoparticle pharmacokinetics and biological effects are influenced by several factors. We assessed the effects of amorphous SiO(2) coating on the pharmacokinetics of zinc oxide nanoparticles (ZnO NPs) following intratracheal (IT) instillation and gavage in rats. METHODS: Uncoated and Si...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Part Fibre Toxicol
Egile Nagusiak: Konduru, Nagarjun V, Murdaugh, Kimberly M, Sotiriou, Georgios A, Donaghey, Thomas C, Demokritou, Philip, Brain, Joseph D, Molina, Ramon M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237897/
https://ncbi.nlm.nih.gov/pubmed/25183210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-014-0044-6
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