Bioavailability, distribution and clearance of tracheally-instilled and gavaged uncoated or silica-coated zinc oxide nanoparticles

BACKGROUND: Nanoparticle pharmacokinetics and biological effects are influenced by several factors. We assessed the effects of amorphous SiO(2) coating on the pharmacokinetics of zinc oxide nanoparticles (ZnO NPs) following intratracheal (IT) instillation and gavage in rats. METHODS: Uncoated and Si...

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Vydáno v:Part Fibre Toxicol
Hlavní autoři: Konduru, Nagarjun V, Murdaugh, Kimberly M, Sotiriou, Georgios A, Donaghey, Thomas C, Demokritou, Philip, Brain, Joseph D, Molina, Ramon M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237897/
https://ncbi.nlm.nih.gov/pubmed/25183210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-014-0044-6
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