CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells

BACKGROUND: Acute myeloid leukemia (AML) remains a difficult disease to treat and requires new therapies to improve treatment outcome. Wee1 inhibitors have been used to prevent activation of the G2 cell cycle checkpoint, thus enhancing the antitumor activity of DNA damaging agents. In this study, we...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Qi, Wenxiu, Xie, Chengzhi, Li, Chunhuai, Caldwell, J Timothy, Edwards, Holly, Taub, Jeffrey W, Wang, Yue, Lin, Hai, Ge, Yubin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237862/
https://ncbi.nlm.nih.gov/pubmed/25084614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0053-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados