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TCR-triggered extracellular superoxide production is not required for T-cell activation

BACKGROUND: In the last decade, reactive oxygen species (ROS) production has been shown to occur upon T-cell receptor (TCR) stimulation and to affect TCR-mediated signalling. However, the exact reactive species that are produced, how ROS are generated and their requirement for T-cell activation, pro...

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Publicat a:Cell Commun Signal
Autors principals: Belikov, Aleksey V, Schraven, Burkhart, Simeoni, Luca
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237797/
https://ncbi.nlm.nih.gov/pubmed/25081034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0050-1
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