TCR activation kinetics and feedback regulation in primary human T cells

BACKGROUND: Signaling through the TCR is crucial for the generation of different cellular responses including proliferation, differentiation, and apoptosis. A growing body of evidence indicates that differences in the magnitude and the duration of the signal are critical determinants in eliciting ce...

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Detalhes bibliográficos
Main Authors: Poltorak, Mateusz, Arndt, Boerge, Kowtharapu, Bhavani S, Reddycherla, Amarendra V, Witte, Vanessa, Lindquist, Jonathan A, Schraven, Burkhart, Simeoni, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842781/
https://ncbi.nlm.nih.gov/pubmed/23317458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-4
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