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Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model

BACKGROUND: We previously reported that Enterovirus 71 (EV71) infection activates autophagy, which promotes viral replication both in vitro and in vivo. In the present study we further investigated whether EV71 infection of neuronal SK-N-SH cells induces an autophagic flux. Furthermore, the effects...

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Détails bibliographiques
Publié dans:J Biomed Sci
Auteurs principaux: Lee, Ying-Ray, Wang, Po-Shun, Wang, Jen-Ren, Liu, Hsiao-Sheng
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237791/
https://ncbi.nlm.nih.gov/pubmed/25139436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-014-0080-4
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