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Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model

BACKGROUND: We previously reported that Enterovirus 71 (EV71) infection activates autophagy, which promotes viral replication both in vitro and in vivo. In the present study we further investigated whether EV71 infection of neuronal SK-N-SH cells induces an autophagic flux. Furthermore, the effects...

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Publicat a:J Biomed Sci
Autors principals: Lee, Ying-Ray, Wang, Po-Shun, Wang, Jen-Ren, Liu, Hsiao-Sheng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237791/
https://ncbi.nlm.nih.gov/pubmed/25139436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-014-0080-4
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