UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication

Positive-strand RNA virus infections can induce the stress-related unfolded protein response (UPR) in host cells. This study found that enterovirus A71 (EVA71) utilizes host UDP-glucose glycoprotein glucosyltransferase 1 (UGGT1), a key endoplasmic reticulum protein (ER) involved in UPR, to enhance v...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Huang, Peng-Nien, Jheng, Jia-Rong, Arnold, Jamie J., Wang, Jen-Ren, Cameron, Craig E., Shih, Shin-Ru
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435352/
https://ncbi.nlm.nih.gov/pubmed/28545059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006375
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