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Sumoylation-promoted Enterovirus 71 3C Degradation Correlates with a Reduction in Viral Replication and Cell Apoptosis

Enterovirus 71 (EV71), a member of the Picornaviridae family, may cause serious clinical manifestations associated with the central nervous system. Enterovirus 3C protease is required for virus replication and can trigger host cell apoptosis via cleaving viral polyprotein precursor and cellular prot...

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Detalhes bibliográficos
Main Authors: Chen, Shu-Chuan, Chang, Luan-Yin, Wang, Yi-Wei, Chen, Yi-Chun, Weng, Kuo-Feng, Shih, Shin-Ru, Shih, Hsiu-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173077/
https://ncbi.nlm.nih.gov/pubmed/21784861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254896
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