Sumoylation-promoted Enterovirus 71 3C Degradation Correlates with a Reduction in Viral Replication and Cell Apoptosis

Enterovirus 71 (EV71), a member of the Picornaviridae family, may cause serious clinical manifestations associated with the central nervous system. Enterovirus 3C protease is required for virus replication and can trigger host cell apoptosis via cleaving viral polyprotein precursor and cellular prot...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Shu-Chuan, Chang, Luan-Yin, Wang, Yi-Wei, Chen, Yi-Chun, Weng, Kuo-Feng, Shih, Shin-Ru, Shih, Hsiu-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173077/
https://ncbi.nlm.nih.gov/pubmed/21784861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254896
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