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Codon optimization and factorial screening for enhanced soluble expression of human ciliary neurotrophic factor in Escherichia coli

BACKGROUND: Neurotrophic factors influence survival, differentiation, proliferation and death of neuronal cells within the central nervous system. Human ciliary neurotrophic factor (hCNTF) has neuroprotective properties and is also known to influence energy balance. Consequently, hCNTF has potential...

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Podrobná bibliografie
Vydáno v:BMC Biotechnol
Hlavní autoři: Itkonen, Jaakko M, Urtti, Arto, Bird, Louise E, Sarkhel, Sanjay
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237735/
https://ncbi.nlm.nih.gov/pubmed/25394427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-014-0092-x
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