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Codon optimization and factorial screening for enhanced soluble expression of human ciliary neurotrophic factor in Escherichia coli
BACKGROUND: Neurotrophic factors influence survival, differentiation, proliferation and death of neuronal cells within the central nervous system. Human ciliary neurotrophic factor (hCNTF) has neuroprotective properties and is also known to influence energy balance. Consequently, hCNTF has potential...
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| Publicado en: | BMC Biotechnol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237735/ https://ncbi.nlm.nih.gov/pubmed/25394427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-014-0092-x |
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