Effect of transporter inhibition on the distribution of cefadroxil in rat brain

BACKGROUND: Cefadroxil, a cephalosporin antibiotic, is a substrate for several membrane transporters including peptide transporter 2 (PEPT2), organic anion transporters (OATs), multidrug resistance-associated proteins (MRPs), and organic anion transporting polypeptides (OATPs). These transporters ar...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Chen, Xiaomei, Loryan, Irena, Payan, Maryam, Keep, Richard F, Smith, David E, Hammarlund-Udenaes, Margareta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237734/
https://ncbi.nlm.nih.gov/pubmed/25414790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-11-25
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