Establishment of CYP2D6 Reference Samples by Multiple Validated Genotyping Platforms

Cytochrome P450 2D6 (cytochrome P450, family 2, subfamily D, polypeptide 6, or CYP2D6), a highly polymorphic drug metabolizing enzyme, is involved in the metabolism of one quarter of the most commonly prescribed medications. Here, we have applied multiple genotyping methods and Sanger sequencing to...

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Vydáno v:Pharmacogenomics J
Hlavní autoři: Fang, Hua, Liu, Xiao, Ramírez, Jacqueline, Choudhury, Noura, Kubo, Michiaki, Im, Hae Kyung, Konkashbaev, Anuar, Cox, Nancy J., Ratain, Mark J., Nakamura, Yusuke, O’Donnell, Peter H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237721/
https://ncbi.nlm.nih.gov/pubmed/24980783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.27
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