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GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy
Seizures frequently accompany gliomas and often escalate to peritumoral epilepsy. Previous work revealed the importance of tumor-derived excitatory glutamate (Glu) release mediated by the cystine-glutamate transporter (SXC) in epileptogenesis. We now show a novel contribution of GABAergic disinhibit...
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| Publicado no: | Glia |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237714/ https://ncbi.nlm.nih.gov/pubmed/25066727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22730 |
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