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Pathway of Human AS3MT Arsenic Methylation

[Image: see text] A synthetic gene encoding human As(III) S-adenosylmethionine (SAM) methyltransferase (hAS3MT) was expressed, and the purified enzyme was characterized. The synthetic enzyme is considerably more active than a cDNA-expressed enzyme using endogenous reductants thioredoxin (Trx), thior...

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Bibliografische gegevens
Gepubliceerd in:Chem Res Toxicol
Hoofdauteurs: Dheeman, Dharmendra S., Packianathan, Charles, Pillai, Jitesh K., Rosen, Barry P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2014
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237493/
https://ncbi.nlm.nih.gov/pubmed/25325836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500313k
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