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A disulfide-bond cascade mechanism for arsenic(III) S-adenosylmethionine methyltransferase

Methylation of the toxic metalloid arsenic is widespread in nature. Members of every kingdom have arsenic(III) S-adenosylmethionine (SAM) methyltransferase enzymes, which are termed ArsM in microbes and AS3MT in animals, including humans. Trivalent arsenic(III) is methylated up to three times to for...

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Bibliografiske detaljer
Udgivet i:Acta Crystallogr D Biol Crystallogr
Main Authors: Marapakala, Kavitha, Packianathan, Charles, Ajees, A. Abdul, Dheeman, Dharmendra S., Sankaran, Banumathi, Kandavelu, Palani, Rosen, Barry P.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356363/
https://ncbi.nlm.nih.gov/pubmed/25760600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004714027552
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