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Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity

[Image: see text] Arsenic methylation, the primary biotransformation in the human body, is catalyzed by the enzyme As(III) S-adenosylmethionine (SAM) methyltransferases (hAS3MT). This process is thought to be protective from acute high-level arsenic exposure. However, with long-term low-level exposu...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Li, Jiaojiao, Packianathan, Charles, Rossman, Toby G., Rosen, Barry P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516783/
https://ncbi.nlm.nih.gov/pubmed/28537708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00113
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