Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein of HRSV, reduced viral replication in challeng...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Schepens, Bert, Sedeyn, Koen, Vande Ginste, Liesbeth, De Baets, Sarah, Schotsaert, Michael, Roose, Kenny, Houspie, Lieselot, Van Ranst, Marc, Gilbert, Brian, van Rooijen, Nico, Fiers, Walter, Piedra, Pedro, Saelens, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237470/
https://ncbi.nlm.nih.gov/pubmed/25298406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404005
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