M2e-Displaying Virus-Like Particles with Associated RNA Promote T Helper 1 Type Adaptive Immunity against Influenza A

The ectodomain of influenza A matrix protein 2 (M2e) is a candidate for a universal influenza A vaccine. We used recombinant Hepatitis B core antigen to produce virus-like particles presenting M2e (M2e-VLPs). We produced the VLPs with and without entrapped nucleic acids and compared their immunogeni...

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Main Authors: Ibañez, Lorena Itatí, Roose, Kenny, De Filette, Marina, Schotsaert, Michael, De Sloovere, Jessica, Roels, Stefan, Pollard, Charlotte, Schepens, Bert, Grooten, Johan, Fiers, Walter, Saelens, Xavier
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601086/
https://ncbi.nlm.nih.gov/pubmed/23527091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059081
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