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SMAR1 coordinates HDAC6-induced deacetylation of Ku70 and dictates cell fate upon irradiation

Acetylation status of DNA end joining protein Ku70 dictates its function in DNA repair and Bax-mediated apoptosis. Despite the knowledge of HDACs and HATs that are reported to modulate the acetylation dynamics of Ku70, very little is known about proteins that critically coordinate these key modifica...

詳細記述

保存先:
書誌詳細
出版年:Cell Death Dis
主要な著者: Chaudhary, N, Nakka, K K, Chavali, P L, Bhat, J, Chatterjee, S, Chattopadhyay, S
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237237/
https://ncbi.nlm.nih.gov/pubmed/25299772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.397
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