Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopes.

The human Factor VIII procoagulant protein (VIII:C) purified from commercial Factor VIII concentrate consisted of a polypeptide doublet of 80,000 mol wt, a 92,000-mol wt polypeptide, and additional polypeptides of up to 188,000 mol wt. Thrombin digests contained a doublet of 72,000 mol wt, as well a...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Fulcher, C A, Roberts, J R, Holland, L Z, Zimmerman, T S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2410456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111933
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