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Purified human factor VIII procoagulant protein: comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogs.

The procoagulant protein F.VIII:C is noncovalently bound to von Willebrand factor (vWF) to give the factor VIII macromolecular complex. New highly purified preparations of isolated human F.VIII:C, devoid of vWF and about 500,000-fold purified, were administered to hemophilia A and von Willebrand dis...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Brinkhous, K M, Sandberg, H, Garris, J B, Mattsson, C, Palm, M, Griggs, T, Read, M S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391515/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3936044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8752
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