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The role of FKBP5 in mood disorders: Action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance

Research on the FKBP5 gene and FKBP51 protein has more than doubled since the discovery that polymorphisms in this gene could alter treatment outcomes and depressive behavior in humans. This coincided with other data suggesting that the stress hormone axis contributes to the development of numerous...

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Détails bibliographiques
Publié dans:CNS Neurol Disord Drug Targets
Auteurs principaux: O’Leary, John C., Zhang, Bo, Koren, John, Blair, Laura, Dickey, Chad A.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236834/
https://ncbi.nlm.nih.gov/pubmed/24040820
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