Demonstration of 26-hydroxylation of C27-steroids in human skin fibroblasts, and a deficiency of this activity in cerebrotendinous xanthomatosis.

26-Hydroxylation of 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol and other C27-steroids was demonstrated in cultured skin fibroblasts from healthy individuals. Activities in skin fibroblasts were approximately 5-10% of those previously found in human liver homogenates, and were inhibited by CO...

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Библиографические подробности
Главные авторы: Skrede, S, Björkhem, I, Kvittingen, E A, Buchmann, M S, Lie, S O, East, C, Grundy, S
Формат: Artigo
Язык:Inglês
Опубликовано: 1986
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC423662/
https://ncbi.nlm.nih.gov/pubmed/3745434
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