Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse

BACKGROUND: Acetaminophen (APAP) is one of the most widely used analgesic and antipyretic pharmaceutical substances in the world and accounts for most cases of drug induced liver injury resulting in acute liver failure. Acute liver failure initiates a sterile inflammatory response with release of cy...

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Bibliographic Details
Published in:BMC Gastroenterol
Main Authors: Steinebrunner, Niels, Mogler, Carolin, Vittas, Spiros, Hoyler, Birgit, Sandig, Catharina, Stremmel, Wolfgang, Eisenbach, Christoph
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236504/
https://ncbi.nlm.nih.gov/pubmed/25139304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-14-148
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