Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse

BACKGROUND: Acetaminophen (APAP) is one of the most widely used analgesic and antipyretic pharmaceutical substances in the world and accounts for most cases of drug induced liver injury resulting in acute liver failure. Acute liver failure initiates a sterile inflammatory response with release of cy...

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Vydáno v:BMC Gastroenterol
Hlavní autoři: Steinebrunner, Niels, Mogler, Carolin, Vittas, Spiros, Hoyler, Birgit, Sandig, Catharina, Stremmel, Wolfgang, Eisenbach, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236504/
https://ncbi.nlm.nih.gov/pubmed/25139304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-14-148
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