Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse

BACKGROUND: Acetaminophen (APAP) is one of the most widely used analgesic and antipyretic pharmaceutical substances in the world and accounts for most cases of drug induced liver injury resulting in acute liver failure. Acute liver failure initiates a sterile inflammatory response with release of cy...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Steinebrunner, Niels, Mogler, Carolin, Vittas, Spiros, Hoyler, Birgit, Sandig, Catharina, Stremmel, Wolfgang, Eisenbach, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236504/
https://ncbi.nlm.nih.gov/pubmed/25139304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-14-148
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